For The Record  

FTR #282 A Shot in the Dark: Designer Genes & the AIDS Vaccine

Lis­ten:
MP3 One Seg­ment
RealAu­dio
NB: This RealAu­dio stream con­tains FTRs 282 and 283 in sequence. Each is a 30-minute broadcast.

Spec­u­la­tive in nature, this pro­gram exam­ines aspects of med­ical research, genetic engi­neer­ing and their appli­ca­tion to the dis­ci­pline of bio­log­i­cal war­fare development.

1. The pro­gram begins with dis­cus­sion of a pro­jec­tion by British med­ical experts. They fore­cast that genetic engi­neer­ing will per­mit the devel­op­ment of “designer” bio­log­i­cal weapons that would take advan­tage of genetic dif­fer­ences between var­i­ous eth­nic groups in order to kill cer­tain spe­cific, tar­geted groups, while leav­ing oth­ers unscathed. (“No Longer Sci­ence Fic­tion! Racially-Targeted Weapons May Become Real­ity Soon;” Reuters; 1/21/1999.)

2. In the con­text of the impend­ing real­ity of ethnically-targeted, genet­i­cally engi­neered bio­log­i­cal weapons, one should con­sider the poten­tial impli­ca­tions of a new drug that has been designed specif­i­cally for African-Americans. (“FDA Paves the Way for First ‘Eth­nic’ Drug” by Vic­to­ria Grif­fith; Finan­cial Times; 3/9/2001; p. 16.)

3. This drug is osten­si­bly designed to pre­vent heart fail­ure. (Idem.)

4. This broad­cast poses an implicit ques­tion. “Might (or has) this tech­nol­ogy been applied in such a way that this (or another) drug might cause heart fail­ure, or some other debil­i­tat­ing or fatal ill­ness?” (There are sub­stan­tive alle­ga­tions that con­tin­gency plans to elim­i­nate African-Americans may be a polit­i­cal real­ity. This also relates to the “sci­ence” of eugenics.)

5. The British mag­a­zine New Sci­en­tist reported that Aus­tralian gene engi­neers had con­verted a mouse­pox virus into a deadly killer. (“Killer Virus: An Engi­neered Mouse Virus Leaves Us One Step away from the Ulti­mate Bioweapon;” New Sci­en­tist; 1/10/2001.)

6. The mouse­pox virus is closely related to the human small­pox virus, and the inser­tion of the mol­e­cule inter­leukin 4 (IL-4) made the rodent ver­sion much dead­lier. (Idem.)

7. Specif­i­cally, the virus destroyed the immune sys­tems of the infected mice, and fit proved resis­tant to a vac­cine that would nor­mally pro­tect mice from infec­tion. (Idem.)

8. Sci­en­tists are afraid that, if IL-4 were added to the human small­pox virus, it could become much dead­lier. (Idem.)

9. Next, the broad­cast sets forth a new, exper­i­men­tal AIDS vac­cine that uti­lizes a mod­i­fied small­pox virus. (“AIDS Vac­cine Shows Promise in Mon­key Exper­i­ments” by Paul Recer [Asso­ci­ated Press]; San Fran­cisco Chron­i­cle; 3/9/2001; p. A13.)

10. In light of the pos­si­bil­ity of genet­i­cally alter­ing the small­pox virus to increase its lethal­ity, as well as the indi­ca­tions that AIDS was dis­trib­uted through an exper­i­men­tal hepati­tis B vac­cine, the use of an altered small­pox vac­cine in an AIDS vac­cine should raise eye­brows. (The prob­a­bil­ity that AIDS stemmed from the appli­ca­tion of genetic engi­neer­ing to bio­log­i­cal war­fare is dis­cussed in numer­ous pro­grams noted above.)

11. It should be noted that this coun­try is par­tic­u­larly vul­ner­a­ble to an out­break of small­pox, due to the rel­a­tive scarcity of the vac­cine. (“The Night­mare of Bioter­ror­ism” by Lau­rie Gar­rett; For­eign Affairs; January/February 2001; p. 77.)

12. In addi­tion, the exist­ing vac­cine has dete­ri­o­rated, ren­der­ing the U.S. all but defense­less against an out­break. (Ibid.; p. 78.)

13. Next, the pro­gram excerpts FTR#212. High­light­ing the man­ner in which the SV40 virus causes can­cer, the pro­gram reviews the role of a pro­tein called large T-antigen in neu­tral­iz­ing the P53 gene. (“The Virus and the Vac­cine” by Debby Bookchin and Jim Schu­macher; The Atlantic Monthly; February/2000.)

14. The p53 gene pre­vents genetic irreg­u­lar­i­ties (and result­ing can­cers) by killing cells that have divided imper­fectly. (Idem.)

15. The fail­ure of this gene fig­ures in a large per­cent­age of can­cers. (Idem.) (The land­mark work of Ed Haslam has high­lighted the role of SV40 in caus­ing can­cer. SV40 was a con­t­a­m­i­nant in the polio vac­cine of the 1950’s. There are numer­ous broad­casts with, or about, the work of Haslam avail­able from Spit­fire. Ed is the author of Mary, Fer­rie and the Mon­key Virus: The Story of an Under­ground Med­ical Lab­o­ra­tory. Copy­right, 1995 by Wordsworth Press.)

16. The ade­n­ovirus (that causes the com­mon cold) also deac­ti­vates the p53 gene. (“A Thank You to the Vol­un­teers Who Step Up for Clin­i­cal Tri­als” by Tom Abate; San Fran­cisco Chron­i­cle; 3/6/2000.)

17. The ade­n­ovirus is being explored as a vehi­cle for “gene ther­apy,” (Idem.) This tech­nique entails the use a virus with altered DNA to inject nucleic acid into dam­aged cells for ther­a­peu­tic purposes.

18. Merck (the com­pany that made the exper­i­men­tal AIDS vac­cine) is now test­ing an AIDS vac­cine that uses a mod­i­fied ade­n­ovirus. (“Merck Starts Human Tri­als of AIDS Vac­cine” by Mark Schoops; Wall Street Jour­nal; 2/22/2001; pp. B1-B4.) At the core of the hypoth­e­sis under­ly­ing this broad­cast, is the cer­tainty that what Mr. Emory calls “the Under­ground Reich” may abuse some of these genetic engi­neer­ing tech­niques in order to pro­duce weapons of mass destruc­tion and/or geno­cide. It should be noted that ele­ments of this Under­ground Reich exist both inside and out­side of gov­ern­ment. They also are deeply involved with the med­ical and phar­ma­ceu­ti­cal industries.

Discussion

No comments for “FTR #282 A Shot in the Dark: Designer Genes & the AIDS Vaccine”

Post a comment