For The Record

FTR #686 Update on the National Cancer Institute’s Viral Cancer Program, Biological Warfare and AIDS

MP3 (One 30-minute seg­ment)
NB: This Flash Audio stream con­tains both FTRs 686 and 687 in sequence. Each is a 30 minute segment.

Intro­duc­tion: The pro­gram begins with a sum­mary intro­duc­tion of the pri­mary sub­ject. After the [offi­cial] aban­don­ment by the U.S. of offen­sive bio­log­i­cal war­fare research, the Nixon admin­is­tra­tion declared a “war on can­cer” in 1971. As part of the War on Can­cer Nixon turned Fort Det­rick (the Army’s top BW research cen­ter) over to the National Can­cer Insti­tute for its Viral Can­cer Project. The Viral Can­cer Project was inex­tri­ca­bly linked with bio­log­i­cal war­fare research and may well have served as a cover for ongo­ing BW work. (Lis­ten­ers inter­ested in this mate­r­ial are encour­aged to check out, among other pro­grams, FTR #‘s 606, 682.)

For the pur­poses of the present dis­cus­sion, it is worth not­ing that it was the National Can­cer Institute’s VCP that was at the epi­cen­ter of AIDS research in the United States.

The VCP/NCI bio­log­i­cal war­fare con­nec­tion uti­lized strong con­nec­tions to uni­ver­sity research facil­i­ties. The Naval Bio­sciences Lab­o­ra­tory (man­aged by the Uni­ver­sity of Cal­i­for­nia), as well as Fort Det­rick were pro­foundly involved with the NCI’s VCP. The Cell Cul­ture Lab­o­ra­tory at the Naval Bio­sciences Facil­ity pro­vided the seed stock for the pro­duc­tion of vast quan­ti­ties of car­cino­genic and immuno­sup­pres­sive viruses that were gen­er­ated by the National Can­cer Institute.

The pro­duc­tion of those viruses for the NCI was over­seen by Drs. James Duff and Jack Gru­ber, both long­time vet­er­ans of Fort Det­rick and its bio­log­i­cal war­fare research.

The aer­ial trans­mis­sion of deadly path­o­genic agents was a major focal point of the NCI’s VCP, appar­ently over­lap­ping BW research projects. Two other key researchers for the NCI, Drs. Alfred Hell­man and Mark Chatigny also had bio­log­i­cal war­fare research back­grounds, includ­ing work with aer­ial trans­mis­sion of path­o­genic agents.

Yet another com­po­nent of the NCI/VCP/BW con­nec­tion was the incor­po­ra­tion of phar­ma­ceu­ti­cal com­pa­nies in the research pro­grams. The Pfizer com­pany pro­duced viruses for the NCI’s VCP, includ­ing the immuno­sup­pres­sive Mason-Pfizer mon­key virus, like HIV, a retrovirus.

Among the most sig­nif­i­cant and alarm­ing aspects of the NCI’s VCP pro­gram is the fact that, when Fort Det­rick was con­verted to the Fred­er­ick Can­cer Research Cen­ter, it was admin­is­tered by Lit­ton Bio­net­ics, a biotech­nol­ogy subi­sidiary of Lit­ton Indus­tries. Lit­ton was a major defense con­trac­tor and a fre­quent vehi­cle for covert operations.

Prior to assum­ing stew­ard­ship of Fort Det­rick for the NCI, Lit­ton Bio­net­ics had employed Dr. Robert Gallo (the “dis­cov­erer” of HIV).

Of para­mount impor­tance in this inves­ti­ga­tion is the fact that the NCI’s VCP pro­gram involved numer­ous exper­i­ments and oper­a­tions designed at get­ting organ­isms to “jump species.” Promi­nent researchers famil­iar with these efforts expressed alarm and the con­vic­tion that such work should be out­lawed, lest it lead to the cre­ation of new, deadly organ­isms that would infect humans.

Obvi­ously, this broad­cast and the line of inquiry approached in Mr. Emory’s decades-long inves­ti­ga­tion of AIDS as a man-made dis­ease high­light the possibility/probability/near cer­tainty that HIV is just such an organism.

Pro­gram High­lights Include: Lit­ton Bio­net­ics’ work on the Mason-Pfizer mon­key virus while under con­tract to the NCI and when it employed Dr. Robert Gallo; research empha­sis on “zoonoses” (dis­eases that jump from ani­mals to humans) by the joint military/civilian con­sor­tium; Gallo’s work with NCI VCP/Ft. Det­rick vet­eran Dr. Jack Gru­ber in a mass viral inoc­u­la­tion pro­gram under­taken by Lit­ton Bio­net­ics; the use of the Mason-Pfizer mon­key virus in the Lit­ton Bio­net­ics mass inoc­u­la­tion program.

1. The pro­gram begins with a sum­mary intro­duc­tion of the pri­mary sub­ject. After the [offi­cial] aban­don­ment by the U.S. of offen­sive bio­log­i­cal war­fare research, the Nixon admin­is­tra­tion declared a “war on can­cer” in 1971. As part of the War on Can­cer Nixon turned Fort Det­rick (the Army’s top BW research cen­ter) over to the National Can­cer Insti­tute for its Viral Can­cer Project. The Viral Can­cer Project was inex­tri­ca­bly linked with bio­log­i­cal war­fare research and may well have served as a cover for ongo­ing BW work.

For the pur­poses of the present dis­cus­sion, it is worth not­ing that it was the National Can­cer Institute’s VCP that was at the epi­cen­ter of AIDS research in the United States.

In 1969, Pres­i­dent Richard Nixon ordered a halt to offen­sive bio­log­i­cal war­fare (BW) research and weapons stock­pil­ing by the United States. The U.S. Army destroyed its tox­ins, viruses, and bac­te­ria with heat and dis­in­fec­tants by May 1972; the dis­posal of the sci­en­tific per­son­nel was not so sim­ple. Some of these biowar­riors went to the CIA.2 Oth­ers quickly found new sup­port from the National Can­cer Insti­tute, par­tic­u­larly in its Virus Can­cer Pro­gram (VCP).3 The NCI funded and super­vised some of the same sci­en­tists, uni­ver­si­ties, and con­tract­ing corporations—ostensibly for can­cer research—which had con­ducted bio­log­i­cal war­fare research. Some of these med­ical research con­tracts ran simul­ta­ne­ously with the U.S. bio­log­i­cal war­fare pro­gram. When the mil­i­tary work ended, the civil­ian pro­grams con­tin­ued to expand on the same crit­i­cal areas out­lined by Colonel Tigertt.

The NCI’s Viral Can­cer Program—a highly politi­cized pub­lic rela­tions effort—was launched in 1971 with great fan­fare as part of Nixon’s War on Can­cer. The stated aim of the pro­gram was to orga­nize exper­i­ments aimed at find­ing cancer-causing viruses.

Appar­ently this agenda was com­pat­i­ble with the incor­po­ra­tion into var­i­ous units of the VCP of pos­si­bly dozens of for­mer U.S. BW researchers who con­tin­ued to study top­ics with poten­tial mil­i­tary appli­ca­tion. Poten­tial cancer-causing viruses were col­lected, grown in huge amounts, and dis­trib­uted through the thou­sands of ani­mals were infected exper­i­men­tally, and the aerosol dis­tri­b­u­tion of car­cino­genic viruses was studied.

“Can­cer War­fare: National Can­cer Insti­tute and the Fort Det­rick Link” by Richard Hatch; Covert Action Infor­ma­tion Bul­letin Num­ber 39 (Win­ter 1991–92).

2. The VCP/NCI bio­log­i­cal war­fare con­nec­tion uti­lized strong con­nec­tions to uni­ver­sity research facil­i­ties. The Naval Bio­sciences Lab­o­ra­tory (man­aged by the Uni­ver­sity of Cal­i­for­nia), as well as Fort Det­rick were pro­foundly involved with the NCI’s VCP. The Cell Cul­ture Lab­o­ra­tory at the Naval Bio­sciences Facil­ity pro­vided the seed stock for the pro­duc­tion of vast quan­ti­ties of car­cino­genic and immuno­sup­pres­sive viruses that were gen­er­ated by the National Can­cer Institute.

The pro­duc­tion of those viruses for the NCI was over­seen by Drs. James Duff and Jack Gru­ber, both long­time vet­er­ans of Fort Det­rick and its bio­log­i­cal war­fare research.

Two for­mer BW facil­i­ties would play a large part in VCP. The U.S. Army’s Fort Det­rick in Fred­er­ick, Mary­land had been the ‘par­ent research and pilot plant cen­ter for bio­log­i­cal warfare.’4 Dur­ing the early 1960s, the CIA paid the facil­ity $100,000 a year for BW and chem­i­cal agents and their deliv­ery sys­tems. In Oak­land, Cal­i­for­nia, the Naval Bio­sciences Lab­o­ra­tory was involved in early exper­i­ments with the plague and col­lab­o­rated in mas­sive open-air tests of bio­log­i­cal war­fare ’sim­u­lants’ in the San Fran­cisco Bay Area in the 1950s. For­mer bio­log­i­cal war­fare spe­cial­ists from both of these cen­ters were deeply involved in all aspects of the VCP.

Reflect­ing a com­mon pat­tern of coop­er­a­tion, much of the military-related research took place at insti­tu­tions con­nected with or directly part of U.S. uni­ver­si­ties. The Uni­ver­sity of Cal­i­for­nia is well known for its role in man­ag­ing the two main U.S. nuclear weapons lab­o­ra­to­ries, the Los Alamos and Lawrence Liv­er­more National Lab­o­ra­to­ries. Less well-known is the fact that UC Berke­ley also helps man­age the Naval Bio­sciences Lab­o­ra­tory (NBL) — ear­lier called the Naval Bio­log­i­cal Lab­o­ra­tory. This con­nec­tion became cen­tral to the VCP and con­tin­ued after the ban on offen­sive BW work.

Well before Pres­i­dent Nixon ordered the con­ver­sion of the U.S. Army BW cen­ter at Fort Det­rick to civil­ian uses in 1971, this mil­i­tary facil­ity was coop­er­at­ing closely with UC.

From 1953 to 1968, the Uni­ver­sity of Cal­i­for­nia, while man­ag­ing the NBL, now at the Naval Sup­ply Cen­ter, also had BW con­tracts with the U.S. Army.5 After U.S treaty oblig­a­tions would have pre­vented open research on mass pro­duc­tion of dan­ger­ous viruses with­out a med­ical “cover”; the VCP pro­vided an ideal excuse to study “scale-up” problems.6

One of the first new pri­or­i­ties of the Fort Det­rick facil­ity after the ban was “the large scale pro­duc­tion of onco­genic [cancer-causing] and sus­pected onco­genic viruses.“7 Within a year, the NCI began mass pro­duc­tion and within one fif­teen month period end­ing in June 1977, the VCP pro­duced 60,000 liters of cancer-causing and immuno­sup­pres­sive viruses.

Through­out the 1970s, U.S. “defen­sive” BW efforts were increas­ingly aimed at the research and devel­op­ment of viral dis­ease agents.8

The “seed stocks” for this mas­sive pro­duc­tion of viruses came from the Cell Cul­ture Lab­o­ra­tory (CCL); the CCL was “phys­i­cally located at the Naval Bio­sciences Lab­o­ra­tory (NBL)” in Oak­land, California.9 Because this lab­o­ra­tory was financed in part by the NCI and linked to UC, it would become a clear­ing­house and cen­tral repos­i­tory for vast quan­ti­ties of poten­tially cancer-causing tis­sues and the tis­sues that might con­tain them. Thus, after the ban, the Naval Bio­sciences Lab at UC con­tin­ued exper­i­men­ta­tion on bio­log­i­cal agents, but under the guise of “defen­sive” research.

The VCP con­tract ran con­cur­rently with the NBL’s work on bubonic plague, Rift Val­ley and menin­gi­tis. The NBL did other research for the Fort Det­rick, before the 1972 ban on offen­sive work. The NBL also per­formed “much of the orig­i­nal research into bio­log­i­cal war­fare dur­ing World War II.” At some NBL work was “listed only in Pen­ta­gon research bulletins.“11

The NBL/Cell Cul­ture Lab­o­ra­tory project was super­vised for the VCP by Drs. James Duff and Jack Gruber.12 Duff had been at Fort Det­rick for 12 years join­ing the NCI. His biog­ra­phy lists research into clostrid­ium bot­u­linum toxins.13 Bot­u­linum tox­ins cause bot­u­lism and are among the most toxic sub­stances known. It was dur­ing Duff’s tenure at Fort Det­rick that the U.S. Army stock­piled bot­u­linum toxin weapons.14 There, too, the inten­sive study of psit­ta­co­sis, or “par­rot fever,” resulted in the acci­den­tal infec­tion of at least 12 workers15 while Duff was work­ing there. After serv­ing for eight years at Fort Det­rick, Gru­ber moved to the NCI. His biog­ra­phy lists work on “arthropod-borne viruses.”16 The U.S. stock­piled BW weapons based on one arthropod-borne virus and stud­ied many oth­ers. He soon became Chair of the Pro­gram Resources and Logis­tics Advi­sory Group of the VCP, where he helped coor­di­nate projects involv­ing pro­duc­tion of viruses, pro­vi­sion of test ani­mals and the ‘bio­haz­ard safety pro­gram.’ 17 In 1984, Gru­ber became head of the Can­cer Eti­ol­ogy Divi­sion of the NIH.

Idem.

3. The aer­ial trans­mis­sion of deadly path­o­genic agents was a major focal point of the NCI’s VCP, appar­ently over­lap­ping BW research projects. Two other key researchers for the NCI, Drs. Alfred Hell­man and Mark Chatigny also had bio­log­i­cal war­fare research back­grounds, includ­ing work with aer­ial trans­mis­sion of path­o­genic agents.

The field of “aer­o­bi­ol­ogy,” or the trans­mis­sion of dis­ease organ­isms through the air, is essen­tially an out­growth of BW research. The mil­i­tary objec­tive of expos­ing many peo­ple to a bio­log­i­cal war­fare agent and the ready sus­cep­ti­bil­ity to infec­tion by inhal­ing these agents make aerosol weapons the most prac­ti­cal form of trans­mis­sion. The NCI also stud­ied aerosol trans­mis­sion of viruses inten­sively. One such study, FS-57 “Aerosol Prop­er­ties of Onco­genic Viruses,” was funded at more than $100,000 a year. After the ban on offen­sive BW research, the NCI and the Office of Naval Research jointly spon­sored NBL exper­i­ments on the “Aerosol Prop­er­ties of Poten­tially Onco­genic Viruses.“18 The NCI jus­ti­fied its aerosol research because its sci­en­tists often han­dled sus­pect can­cer viruses in a highly con­cen­trated form. A lab acci­dent could release a mist of virus; NCI needed to under­stand and antic­i­pate the dan­ger. How the Navy jus­ti­fied its inter­est is unknown, but if a new cancer-causing BW agent was dis­cov­ered, it would likely be deliv­ered as an aerosol.

The line between aerosol and bio­log­i­cal war­fare research was often fine. The NCI project offi­cer and for­mer U.S. Air Force virol­o­gist, Dr. Alfred Hell­man, worked with Mark Chatigny, a research engi­neer at NBL and mem­ber of the NCI bio­haz­ards work group from the NBL.19 Hell­man also over­saw the 1971 $100,000 NBL study on the “phys­i­cal and bio­log­i­cal char­ac­ter­is­tics of viral aerosols..” In 1961, the NBL had done sim­i­lar research for Fort Det­rick on the “sta­bil­ity and vir­u­lence of BW aerosols.“20 Chatigny’s NBL research into aerosol dis­tri­b­u­tion of viruses would con­tinue into the 1980s. Such over­lap­ping of pur­poses raises seri­ous ques­tions about the wis­dom of plac­ing con­trol of VCP viruses under the NBL.

Idem.

4. More about the aerosol stud­ies, over­lap­ping the NCI VCP and involv­ing research done by universities:

While UC Berke­ley appears to have been at the heart of aerosol BW research, it was by no means alone. Other uni­ver­si­ties col­lab­o­rated with the BW effort while work­ing on the VCP in par­al­lel. From 1955 to 1965, the Ohio State Uni­ver­sity Col­lege of Med­i­cine con­ducted research for Fort Det­rick into the aerosol trans­mis­sion of BW agents includ­ing tularemia and Q fever.21 In some of these stud­ies, pris­on­ers from the Ohio State Pen­i­ten­tiary were used as guinea pigs. Between 1952 and 1969, the affil­i­ated Ohio State Uni­ver­sity Research Foun­da­tion had eight con­tracts with the U.S. Army for BW research. Tularemia (“rab­bit fever”) and Q fever were ulti­mately stock­piled by the U.S. Army.22

Before he worked with UC, Dr. Hell­man super­vised an NCI con­tract for Ohio State Uni­ver­sity. Designed to study the aerosol trans­mis­sion of cancer-causing viruses, this research started in 1965 and con­tin­ued at least until 1972. The prin­ci­pal inves­ti­ga­tor for this work, Dr. Richard Griese­mer, would even­tu­ally suc­ceed in giv­ing tumors to mice and mon­keys. Griese­mer then went to work briefly at the Oak Ridge National Lab­o­ra­tory, part of the U.S. Depart­ment of Energy nuclear research sys­tem. After his stint at Oak Ridge, Griese­mer returned to NCI, where he headed the NCI Bioas­say pro­gram, which tested chem­i­cals sus­pected of caus­ing can­cer. This mul­ti­mil­lion dol­lar pro­gram was so badly man­aged that epi­demics forced the killing of nearly 90,000 test ani­mals and test­ing of sus­pected car­cino­genic chem­i­cals fell far behind schedule.23

Many other uni­ver­si­ties promi­nent in the U.S. BW pro­gram, such as Johns Hop­kins, Uni­ver­sity of Mary­land, and the Uni­ver­sity of Min­nesota, were also heav­ily involved in the VCP. Since the BW work per­formed by these uni­ver­si­ties remains clas­si­fied, the exact rela­tion between VCP and bio­log­i­cal war­fare research remains murky.

Idem.

5. Yet another com­po­nent of the NCI/VCP/BW con­nec­tion was the incor­po­ra­tion of phar­ma­ceu­ti­cal com­pa­nies in the research pro­grams. The Pfizer com­pany pro­duced viruses for the NCI’s VCP, includ­ing the immuno­sup­pres­sive Mason-Pfizer mon­key virus dis­cussed in the next major sec­tion of the program.

The pat­tern of over­lap­ping mil­i­tary BW and NCI work was par­al­leled by the rela­tion­ship between indus­trial con­trac­tors and the VCP. Charles Pfizer and Com­pany, Inc., a phar­ma­ceu­ti­cal firm, had a con­tract with the NCI which included pro­duc­tion of “a large quan­tity of a vari­ety of viruses” for the VCP.24 The immuno­sup­pres­sive Mason-Pfizer mon­key virus was grown in large quan­tity, and other ani­mal can­cer viruses were adapted to grow in human cell lines. Dur­ing the same time period—1961 to 1971—the NCI con­trac­tor, Pfizer, con­ducted a secret study for the U.S. Army “into the growth and cul­ture media for unspec­i­fied... bio­log­i­cal agents.“25

In addi­tion, from 1968 to 1970, Pfizer had a con­tract for Scale Pro­duc­tion and Eval­u­a­tion of Staphy­lo­coc­cal Entero­tox­oid B” for the U.S. Army BW program.26 Staphy­lo­coc­cal entero­tox­oid is a pro­tec­tive vac­cine against a bac­te­r­ial toxin which was part of the U.S. arse­nal. The pro­duc­tion of vac­cine against a stock­piled BW weapon must be con­sid­ered an offen­sive BW project Accord­ing to MIT sci­en­tists Harlee Strauss and Jonathan King, “These steps—the gen­er­a­tion of a poten­tial BW agent, devel­op­ment of a vac­cine against it, test­ing of the effi­cacy of the vaccine—are all com­po­nents that would be asso­ci­ated with an offen­sive BW program.“27 Clearly, with­out an anti­dote or vac­cine to pro­tect attack­ing troops, the util­ity of a stock­piled BW agent would be seri­ously limited.

Idem.

6. Among the most sig­nif­i­cant and alarm­ing aspects of the NCI’s VCP pro­gram is the fact that, when Fort Det­rick was con­verted to the Fred­er­ick Can­cer Research Cen­ter, it was admin­is­tered by Lit­ton Bio­net­ics, a biotech­nol­ogy subi­sidiary of Lit­ton Indus­tries. Lit­ton was a major defense con­trac­tor and a fre­quent vehi­cle for covert operations.

Prior to assum­ing stew­ard­ship of Fort Det­rick for the NCI, Lit­ton Bio­net­ics had employed Dr. Robert Gallo (the “dis­cov­erer” of HIV).

” . . . One of Bio­net­ics Research Lab­o­ra­to­ries’ most impor­tant NCI con­tracts was a mas­sive virus inoc­u­la­tion pro­gram that began in 1962 and and ran until at least 1976, and used more than 2,000 mon­keys. Dr. Robert Gallo, the con­tro­ver­sial head of the cur­rent U.S. AIDS research pro­gram at NCI and the chief of its tumor cell biol­ogy lab­o­ra­tory, and Dr. Jack Gru­ber, for­merly of VCP and then NIH, were project offi­cers for the inoc­u­la­tion program. . . .”

Among the pri­mary focal points of Lit­ton Bio­net­ics’ research was the Mason-Pfizer mon­key virus, a simian retro­virus that induces immuno­sup­pres­sion in pri­mates. HIV is a retrovirus.

Pres­i­dent Nixon’s 1971 announce­ment that Fort Det­rick would be con­verted to a cen­ter for can­cer research could not be imme­di­ately imple­mented. First, BW agents stored there, such as the anti-crop agent rice blast, had to be destroyed. The build­ings were then decon­t­a­m­i­nated and the facil­i­ties were turned over to the NCI, which renamed the facil­ity the Fred­er­ick Can­cer Research Cen­ter; Litton-Bionetics was named as the prime con­trac­tor. A major player in the military-industrial com­plex, the cor­po­ra­tion worked exten­sively on the dis­per­sion of BW agents from planes, and included U.S. Air Force con­tracts for “the super­sonic deliv­ery of dry bio­log­i­cal agents.”28 From 1966 to 1968, Bio­net­ics Research Lab­o­ra­to­ries (which became Litton-Bionetics in 1973) held two con­tracts with the U.5. Army BW program.29 At the same time, it held major con­tracts with the NCI.30 One of Bio­net­ics Research Lab­o­ra­to­ries’ most impor­tant NCI con­tracts was a mas­sive virus inoc­u­la­tion pro­gram that began in 1962 and and ran until at least 1976, and used more than 2,000 mon­keys. Dr. Robert Gallo, the con­tro­ver­sial head of the cur­rent U.S. AIDS research pro­gram at NCI and the chief of its tumor cell biol­ogy lab­o­ra­tory, and Dr. Jack Gru­ber, for­merly of VCP and then NIH, were project offi­cers for the inoc­u­la­tion pro­gram. The mon­keys were injected with every­thing from human can­cer tis­sues to rare viruses and even sheep’s blood in an effort to find a trans­mis­si­ble can­cer. Many of these mon­keys suc­cumbed to immuno­sup­pres­sion after infec­tion with the Mason-Pfizer mon­key virus, the first known immuno­sup­pres­sive retrovirus,31 a class of viruses that includes the human immun­od­e­fi­ciency virus.

Idem.

7. Of para­mount impor­tance in this inves­ti­ga­tion is the fact that the NCI’s VCP pro­gram involved numer­ous exper­i­ments and oper­a­tions designed at get­ting organ­isms to “jump species.” Promi­nent researchers famil­iar with these efforts expressed alarm and the con­vic­tion that such work should be out­lawed, lest it lead to the cre­ation of new, deadly organ­isms that would infect humans.

Obvi­ously, this broad­cast and the line of inquiry approached in Mr. Emory’s decades-long inves­ti­ga­tion of AIDS as a man-made dis­ease high­light the possibility/probability/near cer­tainty that HIV is just such an organism.

In 1976, Dr. Sey­mour Kalter, a promi­nent NCI sci­en­tist and for­mer mil­i­tary med­i­cine expert, reported on exper­i­ments so dan­ger­ous that other sci­en­tists pub­licly asked for an end to such work.32 By blend­ing the genetic mate­r­ial of viruses caus­ing can­cers in mice and baboons, he cre­ated a new virus which could cause can­cer in dogs, mon­keys and even chim­panzees. Because it could attack chim­panzees, other sci­en­tists feared it could spread to genet­i­cally sim­i­lar human beings. The new virus was a prod­uct of some of the first crude genetic “recom­bi­na­tion” exper­i­ments. Lawrence Loeb and Ken­neth Tartof of the Insti­tute for Can­cer Research in Philadel­phia, Penn­syl­va­nia, went even fur­ther in call­ing for change and called for a ban on such poten­tially dan­ger­ous experimentation.

The pro­duc­tion of malig­nant tumors in a vari­ety of pri­mate species sug­gests the pos­si­bil­ity of cre­at­ing viruses that are onco­genic for humans… There­fore, we urge that all exper­i­ments involv­ing co-cultivation of known onco­genic viruses with pri­mate viruses be imme­di­ately halted until the safety of such exper­i­ments are [sic] exten­sively evaluated.33

Exper­i­ments per­formed under NCI con­tract included many dan­ger­ous viral inoc­u­la­tion pro­grams, like the pri­mate inoc­u­la­tion pro­gram run by Gallo and Gru­ber. So-called “species bar­ri­ers” were rou­tinely breached in efforts to find or cre­ate infec­tious can­cer viruses. Viruses native to one species were injected into ani­mals from another species in hope of trig­ger­ing can­cers. Often the recip­i­ent ani­mal would be immuno­sup­pressed by radi­a­tion, drugs, or other treat­ments. NIH pri­mate researchers were well aware that “the eco­log­i­cal niches of man and ani­mal cross with increas­ing fre­quency, and this undoubt­edly will cre­ate or uncover new problems.”34

At a 1975 NCI sym­po­sium, a par­tic­i­pant, Dr. J. Moor-Janowski admit­ted that “environmental-motivated, we moti­vated groups begin to con­sider pri­mate lab­o­ra­to­ries as being a source of dan­ger.” He con­tin­ued to com­ment that “a [Euro­pean] pri­mate cen­ter was not able to begin oper­a­tions as a result of adverse pub­lic­ity they obtained because of Mar­burg dis­ease.” The speaker was refer­ring to a 1967 out­break in Yugoslavia and West Ger­many of this viral dis­ease, which killed sev­eral peo­ple. Tis­sues obtained from African Green mon­keys used in bio­med­ical work were the source of the mini-epidemic. Dr. Moor-Janowski sug­gested that researchers should fight against tighter restric­tions on pri­mate exper­i­ments. 35

Idem.

8. In addi­tion, the NCI’s VCP was the foun­da­tion for pro­fes­sional inter­ac­tion between civil­ian med­ical and sci­en­tific researchers and their coun­ter­parts in the mil­i­tary. One obvi­ous out­growth of this would be enhance­ment of the mil­i­tary personnel’s knowl­edge and pro­fes­sional capabilities.

A major focal point of this military/civilian sym­po­sium was “Zoonoses”–diseases that jump from ani­mals to humans. The pro­gres­sion of HIV from mon­key virus to mutated mon­key virus that attacks humans should be eval­u­ated in this context.

Under the National Can­cer Insti­tute aegis, VCP pro­vided many oppor­tu­ni­ties for con­tact between for­mer BW spe­cial­ists and oth­ers in the sci­en­tific com­mu­nity. For­mer BW spe­cial­ists Drs. Peter Gerone and Arnold Wedum were promi­nent mem­bers of the Bio­haz­ard Con­trol and Con­tain­ment Seg­ment of the VCP. Their posi­tions allowed them fre­quent con­tact with lab­o­ra­to­ries han­dling haz­ardous viruses. Gerone and Wedum both worked for many years at Fort Det­rick; they were both spe­cial­ists in the air­borne trans­mis­sion of dis­eases. In the 1950s, Wedum was in charge of U.S. Army tests of tularemia (“rab­bit fever”) on human “vol­un­teers.” In Gerone’s BW research, he used pris­on­ers from the Fed­eral Prison Camp at Eglin Air Force Base in Florida. This group of human guinea pigs was more for­tu­nate than Dr. Wedum’s; they were exposed only to cold viruses. Gerone was awarded the Army’s Mer­i­to­ri­ous Civil­ian Ser­vice Award for his efforts at Fort Detrick.

The 1975 NCI spon­sored sym­po­sium on “Bio­haz­ards and Zoonotic Prob­lems of Pri­mate Pro­cure­ment, Quar­an­tine, and Research“36 illus­trates another aspect of NCI-military coop­er­a­tion. Zoonoses—diseases that can be trans­mit­ted from ani­mals to humans—make up the major­ity of BW agents. The meet­ing brought together NCI researchers, nine mil­i­tary offi­cers from Major to Colonel and a civil­ian from the Edge­wood Arse­nal, a U.S. chem­i­cal war­fare facil­ity, also in Mary­land. The offi­cers were from the U.S. Army Med­ical Research Insti­tute of Infec­tious Dis­eases, the Defense Nuclear Agency and the Armed Forces Insti­tute of Pathol­ogy. In addi­tion, Drs. Wedum, Duff, Gru­ber, and Gerone were all in attendance.

Gerone pre­sented a paper on the “Bio­haz­ards of Exper­i­men­tally Infected Pri­mates”; he now headed Tulane University’s Delta Regional Pri­mate Research Cen­ter. In pass­ing, he men­tioned aerosol haz­ards and rec­om­mended “expos­ing ani­mals so that only the head is in con­tact with the aerosol” rather than using “whole body expo­sure.” Wedum had pre­vi­ously briefed him on BW tests involv­ing just such expo­sure of mon­keys to aerosolized staphy­lo­coc­cal entero­toxin; in these tests four Fort Det­rick work­ers still became ill through expo­sure to the ani­mals. Pre­sum­ably Gerone was also aware of a 1964 acci­dent when 15 Fort Det­rick work­ers inhaled aerosolized staphy­lo­coc­cal entero­toxin B, “mil­ligram for mil­ligram, one of the most deadly agents ever studied.“37

In addi­tion to sym­posia which brought together mil­i­tary and civil­ian spe­cial­ists, the VCP uti­lized con­sul­tants with strong bio­log­i­cal war­fare back­grounds. At times, Dr. Stu­art Madin and Mark Chatigny from the NBL, Peter Gerone, and Arthur Brown were all listed as con­sul­tants to the NCI. Brown, the for­mer head of the Virus and Rick­ettsia Divi­sion of Fort Det­rick, had already been involved in a bla­tant instance of attempted covert recruit­ment of micro­bi­ol­o­gists for BW research.

In 1966, Brown signed a let­ter solic­it­ing research.38 It asked sci­en­tists to sub­mit pro­pos­als to study the recom­bi­na­tion of bac­te­ria, but tried to dis­guise the true source of funding-the Depart­ment of Defense. NCI sci­en­tist Karl Habel also signed the let­ter; Habel was “con­nected with viral research at the National Insti­tutes of Health.“39 The attempt to recruit micro­bi­ol­o­gists to work on recom­bi­na­tion of bac­te­ria fiz­zled after the fund­ing source was pub­licly exposed. That it was attempted at all, shows that NIH sci­en­tists were will­ing to team up with the Fort Det­rick spe­cial­ists in covert oper­a­tions and that some were also will­ing to deceive their col­leagues into col­lab­o­rat­ing with them.

Idem.

9. The arti­cle con­cludes by sum­ma­riz­ing the pro­found and sus­pi­cious degree of over­lap between mil­i­tary BW research projects and the NCI’s VCP:

Research into viruses dur­ing the War on Can­cer pro­vided an ideal cover for con­tin­u­ing bio­log­i­cal war­fare research. As Colonel Tigertt advised, the NCI project allowed the mass pro­duc­tion of viruses, the devel­op­ment of means to enhance vir­u­lence, explo­ration of aerosol trans­mis­sion, and the pro­duc­tion of new recom­bi­nant dis­ease agents. These “civil­ian” projects ran con­cur­rently with “mil­i­tary” projects in many cases. When polit­i­cal expe­di­ency dic­tated an end to overt U.S. BW research, the Viral Can­cer Pro­gram pro­vided a means to con­tinue exper­i­ments that would oth­er­wise be dif­fi­cult to justify.

That the U.S. would covertly con­tinue a BW pro­gram should not be quickly dis­counted. Right up to the start of the VCP, U.S. covert oper­a­tors con­ducted clan­des­tine tests sim­u­lat­ing aerosol BW attacks. The NBL sup­plied per­son­nel, lab facil­i­ties, and equip­ment for a secret 1950 aerosol attack on San Fran­cisco which resulted in dos­ing almost every­one in the city with a BW agent “simulant.“40 Other mil­i­tary exper­i­ments used spe­cial­ized cars and suitcases.41 The Spe­cial Oper­a­tions Divi­sion of the CIA, which oper­ated from Fort Det­rick, engaged in sim­i­lar covert tests using LSD and other chem­i­cal under the MK-ULTRA pro­gram. Another CIA-SOD pro­gram, MK-NAOMI, col­lected bio­log­i­cal tox­ins and disease.42

While Nixon ordered a sup­posed end to BW offen­sive efforts in 1969, the Cen­tral Intel­li­gence Agency retained a secret BW and toxin weapon capability.43 Given this record of decep­tion in the U.S. BW pro­gram, the Viral Can­cer Pro­gram may well have used the search for a cure for can­cer as a cover to con­tinue its exper­i­ments on bio­log­i­cal warfare.

Idem.

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