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FTR#1257 Pandemics, Inc., Part 7 (Too Much Monkeypox Business)

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— George Orwell, 1946

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FTR#1257 This pro­gram was record­ed in one, 60-minute seg­ment.

Stages of Mon­key­pox devel­op­ment
Cred­it: Wikipedia

Intro­duc­tion: This pro­gram con­tin­ues dis­cus­sion and analy­sis of the con­sor­tium of Eco­Health Analy­sis, Metabio­ta, In-Q-Tel and Munich Re–an asso­ci­a­tion inex­tri­ca­bly linked with bio­log­i­cal war­fare and gen­er­a­tion of the Covid-19 pan­dem­ic.

First, we review the fact that Metabiota–which uses AI and social media scrap­ing (among oth­er tools) to gauge the “fear fac­tor” involved with pan­dem­ic readi­ness (and the asso­ci­at­ed pan­dem­ic insur­ance policies)–was gaug­ing the fear fac­tor for mon­key pox, which had man­i­fest­ed some human infec­tions in the Con­go as “low.”

This was in ear­ly 2020. Now, the dis­ease is on the “front burn­er,” so to speak. Peo­ple are afraid of the “new pan­dem­ic.”

Despite only 306 doc­u­ment­ed cas­es in the U.S. (as of 6/28/2022), hun­dreds of thou­sands of vac­cine dos­es are being read­ied for human use.

The dis­ease bears an epi­demi­o­log­i­cal sim­i­lar­i­ty to AIDS: an African mon­key virus infect­ing gay males with mul­ti­ple sex part­ners.

In addi­tion, we review an excerpt­ing of an op-ed col­umn by Scott Got­tlieb, the head of the FDA under Trump, a mem­ber of the con­ser­v­a­tive Amer­i­can Enter­prise Insti­tute and a mem­ber of the board of direc­tors of Pfiz­er.

He notes that the new agency cre­at­ed by Biden to deal with mon­key­pox and oth­er emerg­ing infec­tions was for­mer­ly: ” . . . . an office inside ‌the Depart­ment of Health and Human Ser­vices that is charged with coor­di­nat­ing the fed­er­al response to bioter­ror­ism . . . .

Sam­pling some of the media cov­er­age of the mon­key­pox out­break, Mr. Emory reads from Amer­i­ca’s “News­pa­per of Record,” The New York Times:

“Anoth­er Virus Is Catch­ing Amer­i­ca Off Guard” by Jay K. Var­ma; The New York Times; 6/28/2022; p. A23 [West­ern Print Edi­tion].

“Health Offi­cials Call Emer­gency for Mon­key­pox” by Apoor­va Man­davil­li; The New York Times; 7/24/2022; pp. A1-A23 [West­ern Print Edi­tion].

“Health Sec­re­tary Says States ‘Need to Work with Us’ on Fight­ing Mon­key­pox” by Sheryl Gay Stol­berg and Noah Wei­land; The New York Times; 7/29/2022; p. A‑20 [West­ern Print Edi­tion].

“U.S. Calls Rise of Mon­ey­pox an Emer­gency” by Sheryl Gay Stol­berg and Apoor­va Man­davil­li; The New York Times; 8/5/2022; pp. A1-A15 [West­ern Print Edi­tion].

“In Mon­key­pox, Gay Men Con­front a Health Cri­sis With Echoes of the Past” by Liam Stack; The New York Times; 7/29/2022; p. A‑20 [West­ern Print Edi­tion].

Media cov­er­age of the out­break char­ac­ter­izes mon­key­pox as a dis­ease afflict­ing pri­mar­i­ly gay males with mul­ti­ple sex partners–similar to the epi­demi­ol­o­gy of the ear­ly AIDS out­break.

Much of the broad­cast con­sists of infor­ma­tion indi­cat­ing the pos­si­bil­i­ty of air­borne trans­mis­sion of mon­key­pox. NB: Mr. Emory can­not com­ment def­i­nite­ly on this possibility–he presents this analy­sis to note the pos­si­bil­i­ty.

We con­clude that chil­dren have con­tract­ed the dis­ease, with­out engag­ing in the behav­ior asso­ci­at­ed with the spread of mon­key­pox, although this is appar­ent­ly quite rare.

1. First, we review the fact that Metabiota–which uses AI and social media scrap­ing (among oth­er tools) to gauge the “fear fac­tor” involved with pan­dem­ic readi­ness (and the asso­ci­at­ed pan­dem­ic insur­ance policies)–was gaug­ing the fear fac­tor for mon­key pox, which had man­i­fest­ed some human infec­tions in the Con­go as “low.”

This was in ear­ly 2020. Now, the dis­ease is on the “front burn­er,” so to speak. Peo­ple are afraid of the “new pan­dem­ic.”

Despite only 306 doc­u­ment­ed cas­es in the U.S. (as of 6/28/2022), hun­dreds of thou­sands of vac­cine dos­es are being read­ied for human use.

The dis­ease bears an epi­demi­o­log­i­cal sim­i­lar­i­ty to AIDS: an African mon­key virus infect­ing gay males with mul­ti­ple sex part­ners.

“How AI is bat­tling the coro­n­avirus out­break” by Rebec­ca Heil­weil; Vox; 01/28/2020.

. . . . Sim­i­lar­ly, the epi­dem­ic-mon­i­tor­ing com­pa­ny Metabio­ta deter­mined that Thai­land, South Korea, Japan, and Tai­wan had the high­est risk of see­ing the virus show up more than a week before cas­es in those coun­tries were actu­al­ly report­ed, par­tial­ly by look­ing to flight data. Metabio­ta, like Blue­Dot, uses nat­ur­al-lan­guage pro­cess­ing to eval­u­ate online reports about a poten­tial dis­ease, and it’s also work­ing on devel­op­ing the same tech­nol­o­gy for social media data.

Mark Gal­li­van, Metabiota’s data sci­ence direc­tor, explains that online plat­forms and forums can also give an indi­ca­tion that there’s a risk of an epi­dem­ic. Metabio­ta also claims it can esti­mate the risk of a disease’s spread caus­ing social and polit­i­cal dis­rup­tion, based on infor­ma­tion like an illness’s symp­toms, mor­tal­i­ty rate, and the avail­abil­i­ty of treat­ment. For instance, at the time of this article’s pub­li­ca­tion, Metabio­ta rat­ed the risk of the nov­el coro­n­avirus caus­ing pub­lic anx­i­ety as “high” in the US and Chi­na, but it rat­ed this risk for the mon­key­pox virus in the Demo­c­ra­t­ic Repub­lic of the Con­go (where there have been report­ed cas­es of that virus) as “medi­um.”

It’s hard to know just how accu­rate this rat­ing sys­tem or the plat­form itself can be, but Gal­li­van says the com­pa­ny is work­ing with the US intel­li­gence com­mu­ni­ty and the Defense Depart­ment on issues relat­ed to the coro­n­avirus. This is part of Metabiota’s work with In-Q-Tel, the non­prof­it ven­ture firm asso­ci­at­ed with the Cen­tral Intel­li­gence Agency. But gov­ern­ment agen­cies aren’t the only poten­tial clients of these sys­tems. Metabio­ta also adver­tis­es its plat­form to rein­sur­ance com­pa­nies — rein­sur­ance is essen­tial­ly insur­ance for insur­ance com­pa­nies — that might want to man­age the finan­cial risks asso­ci­at­ed with a disease’s poten­tial spread. . . .

2. We review an excerpt­ing of an op-ed col­umn by Scott Got­tlieb, the head of the FDA under Trump, a mem­ber of the con­ser­v­a­tive Amer­i­can Enter­prise Insti­tute and a mem­ber of the board of direc­tors of Pfiz­er.

He notes that the new agency cre­at­ed by Biden to deal with mon­key­pox and oth­er emerg­ing infec­tions was for­mer­ly: ” . . . . an office inside ‌the Depart­ment of Health and Human Ser­vices that is charged with coor­di­nat­ing the fed­er­al response to bioter­ror­ism . . . .

“Mon­key­pox Is About to Become the Next Pub­lic Health Fail­ure” by Scott Got­tlieb; The New York Times; 7/30/2002.

. . . . It has effec­tive­ly cre­at­ed an agency out of an office inside ‌the Depart­ment of Health and Human Ser­vices that is charged with coor­di­nat­ing the fed­er­al response to bioter­ror­ism, among oth­er things. The reorder­ing puts the new Admin­is­tra­tion for Strate­gic Pre­pared­ness and Response on equal foot­ing with the C.D.C. . . .

3a. Sam­pling some of the media cov­er­age of the mon­key­pox out­break, Mr. Emory reads from Amer­i­ca’s “News­pa­per of Record,” The New York Times:

“Anoth­er Virus Is Catch­ing Amer­i­ca Off Guard” by Jay K. Var­ma; The New York Times; 6/28/2022; p. A23 [West­ern Print Edi­tion].

“Health Offi­cials Call Emer­gency for Mon­key­pox” by Apoor­va Man­davil­li; The New York Times; 7/24/2022; pp. A1-A23 [West­ern Print Edi­tion].

“Health Sec­re­tary Says States ‘Need to Work with Us’ on Fight­ing Mon­key­pox” by Sheryl Gay Stol­berg and Noah Wei­land; The New York Times; 7/29/2022; p. A‑20 [West­ern Print Edi­tion].

“U.S. Calls Rise of Mon­ey­pox an Emer­gency” by Sheryl Gay Stol­berg and Apoor­va Man­davil­li; The New York Times; 8/5/2022; pp. A1-A15 [West­ern Print Edi­tion].

“In Mon­key­pox, Gay Men Con­front a Health Cri­sis With Echoes of the Past” by Liam Stack; The New York Times; 7/29/2022; p. A‑20 [West­ern Print Edi­tion].

3b. Media cov­er­age of the out­break char­ac­ter­izes mon­key­pox as a dis­ease afflict­ing pri­mar­i­ly gay males with mul­ti­ple sex partners–similar to the epi­demi­ol­o­gy of the ear­ly AIDS out­break.

“Show­ing Old Prej­u­dices, U.S. Gov­ern­ment False­ly Asso­ciates Mon­key­pox Out­break with Gays, Bisex­u­als and Africans” by  Mor­gan Artyukhi­na; Covert Action Mag­a­zine8/14/2022.

 Mis­in­for­ma­tion Breeds More Fear of Minor­i­ty Groups Along With Mis­un­der­stand­ing About Dis­ease Itself

Care­less mes­sag­ing by glob­al health agen­cies about the out­break of mon­key­pox virus has cre­at­ed wide­spread pub­lic con­fu­sion, includ­ing asso­ci­at­ing the infec­tious dis­ease with gay and bisex­u­al men and with Africans.

The unwar­rant­ed and need­less sit­u­a­tion is a pub­lic health fail­ure and has cam­ou­flaged the true nature of the out­break, which does not dis­crim­i­nate between races, gen­ders, or sex­u­al­i­ties, pos­ing a greater risk to the U.S. pub­lic at large.

Accord­ing to the U.S. Cen­ters for Dis­ease Con­trol and Pre­ven­tion (CDC), more than 11,177 cas­es of mon­key­pox virus (MPXV) have been detect­ed in the Unit­ed States since May, with near­ly all of them being gay and bisex­u­al men, some­times word­ed as “men who have sex with men (MSM).” Glob­al­ly, more than 31,799 cas­es have been detect­ed across 87 coun­tries, with most of them in the U.S., Spain, the Unit­ed King­dom, and Ger­many.

The dis­ease is close­ly relat­ed to the extinct virus var­i­o­la, which caused small­pox. It was first detect­ed in humans in West Africa in 1970, but has nev­er reached such a wide-scale out­break as present­ly exists. This out­break is dri­ven by the West African clade, which has a mor­tal­i­ty rate of less than 1%. A two-shot vac­cine, Jyn­neos, is pro­duced by Dan­ish com­pa­ny Bavar­i­an Nordic and licensed by the U.S. Food and Drug Admin­is­tra­tion (FDA) to inoc­u­late against mon­key­pox, and small­pox vac­cines are pre­dict­ed to pro­vide pro­tec­tion as well, due to their sim­i­lar­i­ty.

Health offi­cials have clear­ly and repeat­ed­ly stat­ed that every­one can catch mon­key­pox and that it is not sex­u­al­ly trans­mit­ted, mean­ing there is noth­ing unique about gay and bisex­u­al men with respect to the virus. What is unique about queer men is that they are the only ones being test­ed, result­ing in a false pic­ture of the out­break as being either only pos­si­ble among them or that it is being spread by them. . . .

. . . . How­ev­er, some, such as health-ori­ent­ed Boston Globe spin­off Stat News, plain­ly stat­ed that “It is not known how any of these peo­ple con­tract­ed the virus,” not­ing that “trans­mis­sion is thought to occur main­ly through virus-laced droplets, but direct con­tact with lesions or bod­i­ly flu­ids from an infect­ed per­son, or indi­rect con­tact via con­t­a­m­i­nat­ed cloth­ing or linens, can also result in trans­mis­sion.” . . . .

3c. Much of the broad­cast con­sists of infor­ma­tion indi­cat­ing the pos­si­bil­i­ty of air­borne trans­mis­sion of mon­key­pox. NB: Mr. Emory can­not com­ment def­i­nite­ly on this possibility–he presents this analy­sis to note the pos­si­bil­i­ty.

CDC Rigs Its Own Mon­key­pox Case Reports by Not Includ­ing Ques­tions on Air­borne Trans­mis­sion by Lam­bert Strether; Naked Cap­i­tal­ism; 8/15/2022.

This short and sweet post will have two parts. First, I will show that the CDC Mon­key­pox case report form omits any ques­tions about air­borne trans­mis­sion. Then I will show why that’s a bad idea, inex­plic­a­ble giv­en CDC’s pre­vi­ous doc­u­men­ta­tion on this point.

Caveat: I am not say­ing that “Mon­key­pox is air­borne.” To my knowl­edge, we don’t have epi­demi­o­log­i­cal stud­ies of the same qual­i­ty we have with Covid; the kind with seat charts and dia­grams of air­flow (as in the famous Skag­it Val­ley cho­rus study, but with many oth­ers); that is the kind of evi­dence I rate high­est, most of all because such stud­ies show me how to imag­ine the ground and what to do. How­ev­er, we do have suf­fi­cient infor­ma­tion not to rule out air­borne trans­mis­sion alto­geth­er, as I will show. That CDC does this a pri­ori — and at the start of what we all hope is not the start of anoth­er glob­al pan­dem­ic on the order of Covid — is mind-bog­gling, or would be mind-bog­gling if we had not, by this time, had plen­ty of expe­ri­ence with how “The Cen­ters for Dis­ease” oper­ates. They have form.

First, let’s look at the CDC case report, “OMB No. 0920–1011.” We have the “Short Form,” designed to be filled out by state or local health offi­cials. We also have the “Data Dic­tio­nary Code­book” (same OMB num­ber), which doc­u­ments the data­base fields that will be pop­u­lat­ed by Short Form data entry. Both are embed­ded in the Appen­dix to this post. (The name “Short Form” sug­gests the exis­tence of a “Long Form,” prob­a­bly pop­u­lat­ing data­base fields unused by the Short Form, but if such a form exists, I haven’t seen it.

From trans­mis­sion, the key sec­tion in the Short From is “His­to­ry of Pos­si­ble Expo­sures.” Here it is:

As you can see, the struc­tured por­tion of the form (i.e. check­box­es and radio but­tons) does not per­mit any rep­re­sen­ta­tion of air­borne trans­mis­sion (cer­tain­ly not a “fleet­ing con­tact” such as has occurred with Covid); air­borne tran­mis­sion is ruled out a pri­ori[1].

An inter­view­er des­per­ate to some­how cram infor­ma­tion about air­borne trans­mis­sion into the form could use the fol­low­ing text fields (“loca­tion of expo­sure,” “addi­tion­al details”):

How­ev­er, exact­ly because such data would be unstruc­tured and unstan­dard­ized, it’s not like­ly to make it into any reports gen­er­at­ed from the data­base.

We now turn to the Data Dic­tio­nary Code­book. As you can see, fields on the Short Form are mapped to fields in a data­base. Here is an exam­ple of how the doc­u­men­ta­tion is struc­tured:

As you can see, the basic struc­ture is a series of field/value pairs, mutu­al­ly exclu­sive (ORed radio but­tons) or not (AND­ed check­box­es). Hilar­i­ous­ly, I found this field while search­ing for “air” (“prairie”); no such luck. “Prairie Dog” strong­ly sug­gests that the Data Dic­tio­nary dates from no lat­er than 2003, when “All peo­ple infect­ed with mon­key­pox in this out­break became ill after hav­ing con­tact with pet prairie dogs. The pets were infect­ed after being housed near import­ed small mam­mals from Ghana. This was the first time that human mon­key­pox was report­ed out­side of Africa.” But no doubt our think­ing, and our fields, have been updat­ed since that time.

We can also see from this exam­ple that the Code­Book con­tains many fields that are not used in the Short Form. Here is anoth­er exam­ple:

The word “mask” does not appear in the Short Form.

I scanned the entire code­book, and I can’t find any fields that would store data rel­e­vant to air­borne trans­mis­sion in the gen­er­al case. (You can check my work in the Appen­dix.) For exam­ple, the famous Japan­ese 3Cs — closed spaces (with poor ven­ti­la­tion), crowd­ed places (with many peo­ple near­by), and close-con­tact set­tings (such as close-range con­ver­sa­tions), are high­ly struc­tured and would lend them­selves well to rep­re­sen­ta­tion in a data­base. Here are more sug­ges­tions:

We can con­clude, then, that CDC sim­ply is not enquir­ing into air­borne trans­mis­sion of Mon­key­pox. They have ruled it out, a pri­ori. How­ev­er, if you go by exist­ing lit­er­a­ture — includ­ing from the CDC itself — there’s plen­ty of rea­son con­sid­er it a real pos­si­blli­ty. To that lit­er­a­ture we now turn.

* * *

First, from KHN, “CDC Posts, Then Deletes, Guid­ance On Air­borne Risks Of Mon­key­pox“:

The Cen­ters for Dis­ease Con­trol and Pre­ven­tion says it removed the rec­om­men­da­tion that trav­el­ers wor­ried about mon­key­pox should wear a mask because it was caus­ing con­fu­sion. Although pub­lic health offi­cials have been link­ing many of the cas­es in this out­break to close sex­u­al con­tacts, mon­key­pox can also be spread through the air for short dis­tances.

This is one of KHN’s handy wrap-ups. From the New York Times, “Mon­key­pox Can Be Air­borne, Too.” So why not col­lect data on air­borne trans­mi­sion of mon­key­pox, if only to rule it out?

Then there’s Nature, “How does mon­key­pox spread? What sci­en­tists know.” What we “know” seems sol­id:

Sev­er­al stud­ies… show that few peo­ple con­tract the dis­ease from an infect­ed house­hold mem­ber with whom they didn’t have sex­u­al con­tact. This find­ing, paired with the data about viral load, sug­gests that res­pi­ra­to­ry droplets and air­borne par­ti­cles prob­a­bly aren’t the pri­ma­ry trans­mis­sion route… If cor­rob­o­rat­ed by fur­ther research [which CDC has decid­ed not to do, because rea­sons], it could call into ques­tion whether peo­ple should iso­late for the entire dura­tion of infec­tion, which might be dif­fi­cult because the ill­ness seems to take up to a month to resolve, she adds.

But what we “know” melts into air:

Even if the virus can be sex­u­al­ly trans­mit­ted, it’s unclear how large of a role this mode of trans­mis­sion has, com­pared with sim­ply being in close, skin-to-skin con­tact with a per­son or inhal­ing their res­pi­ra­to­ry par­ti­cles [gawd, they can nev­er say “aerosols”] — which also occur dur­ing sex.

Put more point­ed­ly, dur­ing sex — hear me out — peo­ple share air, so any the­o­ry of skin-to-skin con­tact has an enor­mous con­found­ing fac­tor. So why not col­lect data on air­borne trans­mi­sion of mon­key­pox, if only to rule it out?

Now let’s do a (frankly cur­so­ry) review of the lit­er­a­ture on air­borne trans­mis­sion of mon­key­pox.

CDC, “Small­pox & Oth­er Orthopoxvirus-Asso­ci­at­ed Infec­tions.” Here is CDC scrub­bing it:

CDC, “Hos­pi­tal Res­pi­ra­to­ry Pro­tec­tion Pro­gram Toolk­it“:

CDC, “Poten­tial Expo­sure to Per­son with Con­firmed Human Mon­key­pox Infec­tion” (via):

CDC, “Mon­key­pox in the Demo­c­ra­t­ic Repub­lic of the Con­go“:

Cough­ing and sneez­ing is pos­si­bly droplets (loo­gies, bal­lis­tic). Talk­ing (like singing) cer­tain­ly includes aerosols, i.e. trans­mis­sion is air­borne.

But wait, there’s more from the CDC:

GOV.UK, “High con­se­quence infec­tious dis­eases (HCID)“:

And final­ly, Clin­i­cal Infec­tious Dis­eases, “The Clin­i­cal Char­ac­ter­is­tics of Human Mon­key­pox, and Risk Fac­tors for Severe Dis­ease.” Fig­ure 1 lists the upper and low­er res­pi­ra­to­ry tract symp­toms — arguably relat­ed to breath­ing, not touch — the researchers stud­ied.:

Odd­ly, the CDC’s “Short Form” has elim­i­nat­ed all these symp­toms, even cough­ing:

Again, why not col­lect data on air­borne trans­mi­sion of mon­key­pox, if only to rule it out?

 

NOTES

[1] CDC might not be so strong on trans­mis­sion, but hoo boy! Did they lav­ish atten­tion on data struc­tures for gen­der and race (although not, nat­u­ral­ly, prox­ies for class like income or edu­ca­tion lev­el).

3d. Although appar­ent­ly quite rare, chil­dren have con­tract­ed the dis­ease, with­out engag­ing in the behav­ior asso­ci­at­ed with the spread of mon­key­pox.

 

 

 

 

Discussion

One comment for “FTR#1257 Pandemics, Inc., Part 7 (Too Much Monkeypox Business)”

  1. Did you know that the Mon­key­pox vac­cine, Tpoxx, was cre­at­ed by ViroPhar­ma in col­lab­o­ra­tion with USAMRIID, SIGA Tech­nolo­gies and oth­ers? Did you know that the co-founder, chair­man, pres­i­dent and CEO of ViroPhar­ma was Claude H. Nash and before he found­ed ViroPhar­ma he worked for Ster­ling Drug? Ster­ling Drug had many con­nec­tions to both the CIA and the Nazis. The CIA took over Ster­ling Drug after WW2. Ster­ling Drug’s con­nec­tions to the CIA and the Nazis are dis­cussed in Charles High­am’ book from 1984, “Trad­ing with the Ene­my: An Exposé of the Nazi-Amer­i­can Mon­ey Plot, 1933–1949”. Links are attached and list­ed below. https://www.nature.com/articles/nbt0918-781b.epdf?sharing_token=cxx-OTlNU-MvwcxDiNLd09RgN0jAjWel9jnR3ZoTv0OmJSXV5f6qESMSHeJyI77pt_8gTdpYQpMTEYg2hcRpnW1FBE6t_AOoJ759Jt354wWWADlh0ZliRVCmTugm2F4FMo5EUczraLQ8eruIiJgOIQ https://en.wikipedia.org/wiki/Claude_H._Nash https://spitfirelist.com/for-the-record/ftr-1169-the-corporate-foundation-of-the-current-malaise/

    Posted by Michael Giordano | August 28, 2022, 12:19 pm

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